Abstract
COVID-19 was primarily detected in Wuhan of China, in December 2019. So far, SARS-CoV-2 with RNA as a genetic material has undergone mutations giving rise to multiple variants. Mutation of a virus is considered to be a process of adaptation to the environment as a survival strategy. This phenomenon needs to be analyzed scientifically to make the world alert from its probable side effects. Therefore, this review paper focuses on the continuing evolution of SARS-CoV-2 leading to its new form VOC 202012/01.